Controlled release study for captopril by using polymer carboxymethyl cellulose
نویسندگان
چکیده
The present study was done to prepare tablet for captopril (CAP) which used in the treatment of hypertension and heart failure. CAP is mainly absorbed from proximal intestine a lesser extent stomach. tablets were prepared by using polymer carboxymethyl cellulose (CMC) drug release system. buffer solutions use at (pH=12,7.4,8.5) as media similitude acidity index stomach, testiness, blood plasma respective. It accounted concentrations that above–mentioned different temperature (25,30,37,40,45,) C°. extended effect function on releasing drug. polymers increased with degree solution acidity. also studied value stability constant temperature.
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ژورنال
عنوان ژورنال: Ma?alla? Tikr?t li-l-?ul?m al-?irfa?
سال: 2023
ISSN: ['2415-1726', '1813-1662']
DOI: https://doi.org/10.25130/tjps.v22i4.738